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KMID : 0043320030260030237
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Archives of Pharmacal Research
2003 Volume.26 No. 3 p.237 ~ p.243
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The Role of Ascorbic Acid on the Redox Status and the Concentration of Malondialdehyde in Streptozotocin-Induced Diabetic Rats
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Choi HJ
Je HD/Jeong JH/Min YS/Choi TS/Park JH/Shin CY/Sohn UD
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Abstract
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A new unsaturated hydroxy acid was isolated from the stem bark extract of Albizzia julibrissin through repeated silica gel and Sephadex LH-20 column chromatography. The chemical structure of the new acid was determined as ( E)-4-hydroxy-dodec-2-enedioic acid on the basis of several spectral data including 2D-NMR. The stereochemical feature of the double bond was determined to be E on the basis of the coupling pattern of related proton signals in the 1H-NMR and COSY experiments.
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